DIENSTAG, 28. APRIL 2026

The Daily

April packt schon die Mai-Tasche.

Wien heute: 🌤️ teils bewölkt, aktuell 15°C (gefühlt 15°C). Wind 11 km/h aus Nordost, Luftfeuchtigkeit 36%. Sonnenaufgang 05:41, Sonnenuntergang 20:04.

NBA

One playoff replay stands above the rest

Last night brought Detroit–Orlando, Oklahoma City–Phoenix and Minnesota–Denver. No scores, no winners, no series math here: the safe takeaway is watchability. If Robert only has time for one replay, Detroit–Orlando is the clear candidate, with Wikihoops showing the strongest signal; the other two look more like context games unless time is generous.
Source: Wikihoops + NBA.com

Boston’s late-clock threes shape Game 5

John Schuhmann’s preview turns Celtics–Sixers into a shot-profile story. Boston keeps living from deep, especially late in possessions, while Philadelphia needs Paul George’s two-way stability and a cleaner fit around Joel Embiid. Useful because it explains playoff offense, not just momentum.
Source: NBA.com

Knicks–Hawks turns on size and McCollum

Shaun Powell’s Game 5 preview is built around a simple tension: Atlanta needs CJ McCollum’s shotmaking to keep bending coverages, while New York can press its size edge with Karl-Anthony Towns and Mitchell Robinson. Good grid story because the star angle and the matchup math point in the same direction.
Source: NBA.com

Wembanyama faces the closing lesson

The Spurs have Wembanyama back in the rhythm after his brief concussion absence, and the next question is more developmental than spectacular. Can a young group manage the pressure of finishing a playoff chapter cleanly? NBA.com also notes Portland’s possible Robert Williams III adjustment, which gives the preview a real basketball hinge.
Source: NBA.com

Biotech & Pharma

Lilly buys Ajax for a better JAK bet

Lilly is acquiring Ajax Therapeutics in a deal worth up to $2.3bn, centered on AJ1-11095 for myelofibrosis. The drug is designed to bind an inactive JAK2 conformation, a mechanistic attempt to get around resistance and durability limits seen with current JAK inhibitors. The point is not just M&A volume; Lilly is buying a hematology mechanism before proof-of-concept data can make it more expensive.
Source: BioPharma Dive

Cell rejuvenation reaches first human tests

The NYT separates rejuvenation biology from longevity marketing by focusing on controlled cellular reprogramming. The news hook is concrete: first human safety trials began in March, starting with an eye-disease approach aimed at glaucoma. The useful frame is disease modification first, youth claims later.
Source: NYT

GLP-1s make food noise researchable

Patients on GLP-1 drugs keep describing the same thing: the internal buzz around eating goes quiet. Researchers who once measured dose, weight and cardiometabolic endpoints are now asking whether “food noise” can reveal something deeper about set-point biology and obesity mechanisms.
Source: NYT

Novartis keeps watching in-vivo CAR-T

Fierce reports that Novartis is still evaluating in-vivo CAR-T approaches, but without an active deal in the works. That makes this a watchlist item rather than a breakthrough: after the cost and infrastructure of ex-vivo CAR-T, the unresolved question is whether in-vivo programming can change access and scale.
Source: Fierce Biotech

Science / Immuno-Oncology

BCMA CAR-T needs sharper myeloma staging

A retrospective study of 158 relapsed or refractory myeloma patients validates the updated consensus genomic staging criteria after BCMA CAR-T. The stronger contribution is the proposed refinement with LDH and extramedullary disease: median PFS ranges from 35.0 months in the lowest-risk group to 6.6 months in the highest-risk group, with estimated 24-month OS from 90% down to 26%.
Source: Blood Cancer Journal / PubMed 42020379

Glofitamab shows a CNS lymphoma signal

In 16 adults with relapsed or refractory primary CNS lymphoma, glofitamab monotherapy produced a 75% interim response rate and 50% complete responses. The intriguing part is pharmacology and monitoring: the CD20×CD3 antibody was detectable in CSF in 60% of patients, and serial CSF ctDNA tracked response and early progression signals.
Source: American Journal of Hematology / PubMed 42035265

Lupus pregnancy is possible, not simple

The NYT case story shows how counseling in lupus pregnancy has changed without making the risk disappear. Lupus nephritis with compromised kidney function remains high-risk medicine, but better treatment and coordinated maternal-fetal, nephrology and autoimmune care now create more room than the old blanket advice to avoid pregnancy.
Source: NYT

Contagious yawning remains oddly mysterious

Der SPIEGEL macht aus Gähnen ein kleines Stück gute Alltagswissenschaft. Menschen gähnen im Schnitt etwa neunmal täglich, viele Wirbeltiere tun es ebenfalls, und trotzdem gilt das Verhalten in Reviews als erstaunlich schlecht verstanden. Der interessante Kern ist die soziale Ansteckung — und die Frage, warum manche Menschen weniger darauf reagieren.
Source: Spiegel+

Wien für Kinder

Donaurauschen im ZOOM

„Donaurauschen und Flussgeflüster“ ist der beste heutige Kinder-Pick, weil er Wien, Naturraum und Ausstellung verbindet. Es geht um den Fluss, der die Stadt prägt, nicht um bloßes Indoor-Bespaßen. Heute um 15:30 Uhr im ZOOM Kindermuseum, MuseumsQuartier, Museumsplatz 1, 1070 Wien — ein ruhiger, konkreter Nachmittagsanker.
Source: FALTER

Pettersson und Findus im Volkstheater

Ein Wochenend-Vormerker für Familien, die lieber eine vertraute Geschichte als Eventlärm wollen. Die Dunkelkammer des Volkstheaters bringt Pettersson, Findus und Bilderbuchwärme auf die Bühne. Sonntag, 3. Mai, 16:00 Uhr, Volkstheater/Dunkelkammer, Arthur-Schnitzler-Platz 1, 1070 Wien.
Source: FALTER

Vivaldi für kleine Ohren

„Klassik Cool!“ macht Vivaldis Jahreszeiten für Kinder von 2 bis 6 Jahren greifbar: mitmachen, hören, Jahreszeiten spüren. Das ist kein stilles Erwachsenenkonzert im Kinderformat, sondern ein klar adressierter Einstieg. 10. Mai, 10:30 Uhr, Bezirksmuseum Josefstadt, Schmidgasse 18, 1080 Wien.
Source: FALTER

Kinderlieder im Niedermair

Bernhard Fibichs „Kuddelmuddel und Gesprudel“ ist ein niederschwelliger Freitag-Nachmittag für Kinder, die lieber mitsingen als stillsitzen. Neue und alte Kinderlieder, Kabarett Niedermair statt Großhalle. Freitag, 1. Mai, 16:00 Uhr, Kabarett Niedermair, Lenaugasse 1a, 1080 Wien.
Source: FALTER